Courteney Cox is set to reunite with her former "Friends" co-star Matthew Perry as she guest stars on an episode set to air in April

It will be the first time Perry, who stars in "Go On," will act alongside Cox since "Friends" went off the air in 2004.

Cox has shared the screen with her "Friends" co-stars several times since the series ended. Jennifer Aniston and Lisa Kudrow made guest appearance on her current show "Cougar Town."