The Game Brawls at Lil Wayne Birthday Party

Sources at the party tell TMZ ... Game was in Hollywood Thursday night with Sean Kingston and the b-day boy himself. We're told Game was allegedly minding his own business when rapper 211 approached and, according to our sources, started talking smack.

We're told things escalated and the smack-talking turned into an all out fight ... which ended with Game allegedly punching 211.

TMZ obtained video just seconds after the fists stopped flying and you can see the two rappers still going at it as security guards rush in to break them up. We're told after security got a hold of the situation, Game was kicked out of the event.